by Stuart Davis | Oct 26, 2019 | Bioinformatics
Trimming for adaptors and low quality bases is important part of the analysis pipeline for sequencing data. Typically, after you isolate and fragment your RNA sample, adaptors are attached to the ends of the sequences that are needed for sequencing (see [1,2] for more...
by Amit | Apr 11, 2019 | Bioinformatics
Audits are probably the most dreaded aspect of NGS data analysis, and like specters, they come in many forms to haunt you. You might need to publish results from several years back, only to realize that the open source tools you used have dramatically changed, forcing...
by Stuart Davis | Mar 5, 2019 | Bioinformatics
Background One of the most popular tools for pathway enrichment analysis for RNA-seq and microarray data is the Gene Set Enrichment Analysis (GSEA) tool by the Broad Institute [1,2]. The database of pathways most often used with GSEA is MSigDB, also by the Broad...
by Stuart Davis | Sep 13, 2018 | Announcements
TATAA Biocenter, the world’s foremost organizer of hands-on training in molecular diagnostics and Europe’s leading provider of genomic services, has partnered with us, Basepair. We are a leading provider of Next Generation Sequencing (NGS) data analysis...
by Amit | Jul 3, 2018 | Announcements
Basepair was founded in direct response to the challenges I was personally facing with Next Generation Sequencing (NGS) analysis while working at Harvard Medical School and other research institutions. NGS has witnessed a data deluge three times larger than...
