by Charles Murphy | Oct 26, 2018 | Bioinformatics
Trimming for adaptors and low quality bases is important part of the analysis pipeline for sequencing data. Typically, after you isolate and fragment your RNA sample, adaptors are attached to the ends of the sequences that are needed for sequencing (see [1,2] for more...
by Stuart Davis | Aug 27, 2016 | Bioinformatics
The performance of NGS alignment tools has continuously improved, but sorting the aligned data now takes more time than alignment. A big leap in sorting was recently initiated with SAMtools version 1.x, with support for parallel processing for sorting. We compared the...
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