by Stuart Davis | Sep 12, 2022 | Bioinformatics
Is it necessary to do base quality score recalibration (BQSR) in the GATK pipeline? How should this be done without an available vcf file of known sites? (a) Unfortunately the quality scores produced by next generation sequencing instruments are subject to...
by Stuart Davis | Aug 27, 2022 | Bioinformatics
Cell and Gene Therapy Biotechnology Company Case Study Time is everything for a bioinformatician. With an active R&D group constantly creating new datasets that need to be analyzed, keeping up with their requests is an uphill battle. The newly...
by Stuart Davis | Mar 18, 2022 | Announcements
With a large number of companies and universities taking extensive measures to curb the spread of COVID-19, many employees are now working remotely. A range of software tools help remote teams seamlessly manage messages, meetings, and projects. Slack for messaging,...
by Stuart Davis | Feb 6, 2022 | Announcements
FASTQ files. Except they’re not “just” files, not “just” data. They’re the culmination of countless hours of running experiments, library preparation, sequencing, etc. You spent all this time gathering data — probably more time than you would have liked — so by the...
by Stuart Davis | May 7, 2021 | Bioinformatics
Introduction In the quest to understand the very blueprint of life, DNA sequencing stands as a pivotal technology. With the advent of high-throughput sequencing methods, we’ve entered an era where decoding the genetic material is more accessible than ever. This...
