Blog
How automated workflows simplify NGS analysis
NGS Data Analysis Bottlenecks One of the biggest bottlenecks in next generation sequencing (NGS) today is data analysis, which is surprising considering that we have massive compute available at our fingertips, the available infrastructure to process thousands of...
Meet Basepair at Bio-IT World 2019
Basepair will be at this year’s Bio-IT World Meet Basepair in Boston, MA from April 16-18, and connect with us to learn how you can run NGS analysis at scale. Our platform is trusted by top institutions such as Partners Healthcare, Harvard Medical School, NYU,...
Performing pathway enrichment with non-human species
Background One of the most popular tools for pathway enrichment analysis for RNA-seq and microarray data is the Gene Set Enrichment Analysis (GSEA) tool by the Broad Institute [1,2]. The database of pathways most often used with GSEA is MSigDB, also by the Broad...
An Update From Basepair!
We at Basepair are thrilled to announce some very good news. We have been selected to participate in Entrepreneurs Roundtable Accelerator’s Summer 2017 program for the next four months. This program entails 100,000 dollars of investments, a great working space, and...
TATAA Biocenter partners with Basepair to offer faster NGS data analysis
TATAA Biocenter, the world's foremost organizer of hands-on training in molecular diagnostics and Europe's leading provider of genomic services, has partnered with us, Basepair. We are a leading provider of Next Generation Sequencing (NGS) data analysis solutions, to...
Faster sorting of BAM files: SAMtools vs sambamba
The performance of NGS alignment tools has continuously improved, but sorting the aligned data now takes more time than alignment. A big leap in sorting was recently initiated with SAMtools version 1.x, with support for parallel processing for sorting. We compared the...
Basepair turns 2.0
Basepair was founded in direct response to the challenges I was personally facing with Next Generation Sequencing (NGS) analysis while working at Harvard Medical School and other research institutions. NGS has witnessed a data deluge three times larger than Moore's...