Basepair Blog
Preparing your NGS data for reproducibility and auditing
Audits are probably the most dreaded aspect of NGS data analysis, and like specters, they come in many forms to haunt you. You might need to publish results from several years back, only to realize that the open source tools you used have dramatically changed, forcing...
Basepair API features
We’ve heard the war stories from our fellow bioinformaticians and lab directors: waking up bleary-eyed in the middle of the night to check on the results of an NGS data analysis pipeline, converting files to different formats, setting up the next step of their...
Visualizing your NGS results with Basepair
Writers write, painters paint, genomics researchers… wait patiently for algorithm pipelines to finish processing NGS data, only to spend as much time visualizing results? As long-time researchers and bioinformaticians, we’re well aware that in NGS data analysis, every...
How automated workflows simplify NGS analysis
NGS Data Analysis Bottlenecks One of the biggest bottlenecks in next generation sequencing (NGS) today is data analysis, which is surprising considering that we have massive compute available at our fingertips, the available infrastructure to process thousands of...
Meet Basepair at Bio-IT World 2019
Basepair will be at this year’s Bio-IT World Meet Basepair in Boston, MA from April 16-18, and connect with us to learn how you can run NGS analysis at scale. Our platform is trusted by top institutions such as Partners Healthcare, Harvard Medical School, NYU,...
Performing pathway enrichment with non-human species
Background One of the most popular tools for pathway enrichment analysis for RNA-seq and microarray data is the Gene Set Enrichment Analysis (GSEA) tool by the Broad Institute [1,2]. The database of pathways most often used with GSEA is MSigDB, also by the Broad...