Blog
Welcome to the Basepair blog, your go-to source for the latest news and insights in genomics research. Our team of experts regularly publish articles and case studies on a wide range of topics, from new technologies and emerging trends to best practices and tips for successful genomic analysis. Whether you’re a seasoned researcher or just starting out in the field, our blog is designed to keep you informed and up-to-date with the latest developments in genomics.
Navigating NGS Data Analysis on AWS: Key Considerations for New-To Sequencing Life Sciences Organizations
Introduction Congratulations on your investment in a new sequencing instrument! You now hold the key to unlocking the secrets hidden within the vast world of genomics. But the journey doesn’t end with data generation; it begins there. To effectively harness the...
The Hidden Limitation of Bioinformatics
The Problem Bioinformatics has hit a ceiling. There are only three ways to analyze the volume of genomic data being produced in the world's research labs by today's modern sequencers from Illumina and newer instrument manufacturers such as Element Biosciences,...
How automated workflows simplify NGS analysis
NGS Data Analysis Bottlenecks One of the biggest bottlenecks in next generation sequencing (NGS) today is data analysis, which is surprising, considering that we have massive compute available at our fingertips, the available infrastructure to process thousands of...
Use of NGS in Cell and Gene Therapy
Introduction Cell and gene therapy have emerged as promising approaches for the treatment of various diseases. These innovative therapies involve manipulating cells or genes to restore or enhance their function. Next-Generation Sequencing (NGS) plays a crucial role in...
A Comprehensive Guide to Analyze Single-Cell RNA Sequencing Data
How to Analyze Single-Cell RNA Sequencing Data: A Comprehensive GuideIntroduction The first step in analyzing scRNA-seq data is to understand the biology behind the experiment. scRNA-seq generates gene expression data for each cell, which can be used to identify cell...
Achieving data provenance with Basepair’s automated audit trails
When Auditing goes wrong Is your genomics team keeping track of the open source tools it’s using? What about software version numbers and the parameters being set? Genome reference files, usage logs, the custom scripts bioinformaticians are deploying? If you’re not...
Visualizing your NGS results with Basepair
Writers write, painters paint, genomics researchers… wait patiently for bioinformatics pipelines to finish processing NGS data, only to spend as much time visualizing results? As long-time researchers and bioinformaticians, we’re well aware that in NGS data analysis,...